Title:
新規ベンズイミダゾール-2-オン誘導体及びその使用方法
Document Type and Number:
Japanese Patent JP2005533814
Kind Code:
A
Abstract:
Certain 1,5-disubstituted benzimidazol-2-one compounds useful as therapeutic agents. The compounds may be of the Formula I wherein: R' represents hydrogen or alkyl; R'' represents halogen or trihalogenmethyl; and Hlg represents halogen; provided, however, that if Hlg is F, then R'' is not Cl. Also, use of the 1,5-disubstituted benzimidazol-2-one compounds, or pharmaceutically-acceptable addition salts thereof, in applications that benefit from increasing the blood-brain barrier permeability.
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Inventors:
Madsen Lars Sime
Bake Camilla Eltebelu
Lauridsen Annette
Auresen Seiren Peter
Bake Camilla Eltebelu
Lauridsen Annette
Auresen Seiren Peter
Application Number:
JP2004516508A
Publication Date:
November 10, 2005
Filing Date:
June 17, 2003
Export Citation:
Assignee:
Poseidon Pharmaceuticals Actieselskabu
International Classes:
A61K31/4184; A61K45/00; A61P9/00; A61P9/10; A61P9/12; A61P11/00; A61P43/00; C07D235/26; (IPC1-7): C07D235/26; A61K31/4184; A61K45/00; A61P9/00; A61P9/10; A61P9/12; A61P11/00; A61P43/00
Attorney, Agent or Firm:
Mitsufumi Esaki
Tsuneo Mihara
Okumura Yoshimichi
Blacksmith
Tsuneo Mihara
Okumura Yoshimichi
Blacksmith