Title:
新規なベンゾチアゼピン及びベンゾチエピン化合物
Document Type and Number:
Japanese Patent JP4711953
Kind Code:
B2
Abstract:
A pharmaceutical useful as a therapeutic agent and a preventive agent for hyperlipemia, and a pharmaceutical useful as a therapeutic agent and a preventive agent for hepatic disorders associated with cholestasis, particularly, primary biliary cirrhosis and primary sclerosing cholangitis, and a pharmaceutical useful as a therapeutic agent and a preventive agent for obesity, fatty liver and steatohepatitis are provided. A benzothiazepine or benzothiepine compound represented by the following formula (1A) having a thioamide bond and a quaternary ammonium substituent:
Inventors:
Takehiko Sasahara
Mori Mori
Kenichi Kasahara
Mori Mori
Kenichi Kasahara
Application Number:
JP2006510539A
Publication Date:
June 29, 2011
Filing Date:
February 25, 2005
Export Citation:
Assignee:
Asahi Kasei Pharma Co., Ltd.
International Classes:
C07D281/10; A61K31/22; A61K31/366; A61K31/38; A61K31/381; A61K31/395; A61K31/4025; A61K31/428; A61K31/439; A61K31/44; A61K31/4995; A61K31/5375; A61K31/541; A61K31/554; A61K45/00; A61P1/16; A61P3/04; A61P3/06; A61P9/04; A61P9/10; A61P43/00; C07D285/36; C07D337/08; C07D409/12; C07D417/12; C07D453/02; C07D471/08; C07D487/08
Domestic Patent References:
| JP2002536440A | 2002-10-29 | |||
| JP2002541248A | 2002-12-03 | |||
| JP2002533413A | 2002-10-08 |
Foreign References:
| WO2002050051A1 | 2002-06-27 | |||
| WO2002008211A2 | 2002-01-31 |
Attorney, Agent or Firm:
Yoshikazu Iwase
Makoto Ono
Kenkyo Kanayama
Yasufumi Shiroyama
Makoto Ono
Kenkyo Kanayama
Yasufumi Shiroyama