Title:
NEW CHOLESTEROL ESTERASE INHIBITOR
Document Type and Number:
Japanese Patent JPH0770102
Kind Code:
A
Abstract:
PURPOSE: To obtain a new cholesterol esterase inhibitor, F1839-M, useful as a therapeutic agent for hyperlipemia, having excellent inhibitory activity against cholesterol esterase.
CONSTITUTION: F1839-M, 6,7-diformyl-4-hydroxy-2,3-dihydrobenzofuran-2- spiro-5'-(2'-hydroxy-1',1',4'a,6'-tetramethyl-1',2',3',4',4'a,5',6',7',8',8'a- decahydronaphtnalene). F1839-M of he formula is obtained by culturing Stachybotrys sp. F-1,839 (FERM P-12,818), a fungus belonging to the genus Stachybotrys, capable of producing F1839-M, collecting F1839-M from the culture solution.
Inventors:
ENDO AKIRA
TSUJI NORITOSHI
MASUDA KAZUO
WATANABE KAZUO
SAKAI KAORU
HASUMI KEIJI
TSUJI NORITOSHI
MASUDA KAZUO
WATANABE KAZUO
SAKAI KAORU
HASUMI KEIJI
Application Number:
JP21841393A
Publication Date:
March 14, 1995
Filing Date:
September 02, 1993
Export Citation:
Assignee:
TOKYO TANABE CO
International Classes:
A61K31/34; A61P3/06; C07D307/94; C12N9/99; C12P17/04; C12R1/645; (IPC1-7): C07D307/94; A61K31/34; C12P17/04
Attorney, Agent or Firm:
Matsuyama Go straight (1 person outside)
Next Patent: 回転ヘッド型記録再生装置