Title:
新規なクリプトフィシン類
Document Type and Number:
Japanese Patent JPH09510436
Kind Code:
A
Abstract:
A cryptophycin compound is provided having the structure: Further provided are methods of producing cryptophycins by total synthesis and methods of using cryptophycins in pharmaceuticals. It is a further object of this invention to use cryptophycins to inhibit the proliferation of mammalian cells. Moreover, methods of using cryptophycins to treat neoplasia is also provided.
Inventors:
Valery Otte, Frederic A.
A corvette, Thomas H.
Smith, Charles Dee.
Paterson, Gregory M. El.
Moore, Richard E.
ムーベリー, Susan El.
A corvette, Thomas H.
Smith, Charles Dee.
Paterson, Gregory M. El.
Moore, Richard E.
ムーベリー, Susan El.
Application Number:
JP51757995A
Publication Date:
October 21, 1997
Filing Date:
December 21, 1994
Export Citation:
Assignee:
Wayne The State A university
A university オブ Hawaii
A university オブ Hawaii
International Classes:
A61K31/195; A61K31/215; A61K31/335; A61K31/336; A61K31/34; A61K31/341; A61K31/395; A61K38/43; A61K45/00; A61P35/00; A61P35/02; A61P43/00; C07C237/22; C07D273/00; C12P13/00; C07D273/08; C07D303/36; C07D307/20; C07D413/06; C07J21/00; C12P21/04; (IPC1-7): C07C237/22; A61K31/195; A61K31/215; A61K31/335; A61K31/34; A61K31/395; A61K38/43; A61K45/00; C07D273/08; C07D303/36; C07D307/20; C07D413/06; C07J21/00; C12P13/00
Attorney, Agent or Firm:
Yusuke Hiraki (besides two persons)