NEW EFFECTIVE TERMINAL DIFFERENTIATION INDUCER AND METHOD FOR USING THE SAME

Japanese Patent JP2007291110

A

To provide a new compound selectively inducing terminal differentiation of tumorous cells.

The compound is represented by formula (I) (wherein, R1and R2are each a cycloalkylamino, a pyridineamino, a piperidino, a 9-purine-6-amine or a thiazoleamino group; R3and R4are each a hydrogen atom, a hydroxy group, a substituted alkyl, an alkenyl, a cycloalkyl, an aryl, an alkyloxy, an aryloxy, an arylalkyloxy or a pyridine group; and n is an integer of 4-8).

COPYRIGHT: (C)2008,JPO&INPIT

WO/1995/015959	TRICYCLIC DERIVATIVES AND THEIR USE IN PHARMACEUTICALS
JPS63165351	POLYCARBOXILIC ACID AND POLYCARBOXYLATE AND UTILIZATION THEREOF AS SURFACTANT AND EMULSIFIER

BRESLOW RONALD
MARKS PAUL A
RIFKIND RICHARD A
JURSIC BRANKO

JP2007114876A

November 08, 2007

April 24, 2007

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SLOAN KETTERING INST CANCER
UNIV COLUMBIA

C07C233/05; A61K31/16; C07D295/18; A61K31/164; A61K31/165; A61K31/167; A61K31/192; A61K31/194; A61K31/197; A61K31/20; A61K31/216; A61K31/221; A61K31/225; A61K31/275; A61K31/277; A61K31/425; A61K31/426; A61K31/427; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/445; A61K31/4453; A61K31/52; A61P35/00; A61P35/02; A61P43/00; C07C229/24; C07C229/30; C07C233/06; C07C233/07; C07C233/15; C07C233/25; C07C233/34; C07C233/36; C07C233/43; C07C233/54; C07C233/64; C07C233/92; C07C237/04; C07C237/30; C07C237/42; C07C255/19; C07C255/30; C07C255/42; C07C255/44; C07C255/60; C07C259/06; C07C259/08; C07C259/10; C07C271/10; C07C271/28; C07C275/28; C07D211/16; C07D211/26; C07D211/32; C07D213/56; C07D213/75; C07D277/02; C07D277/20; C07D277/44; C07D277/46; C07D295/185; C07D487/04; C07D519/00

Takehiko Suzue
Satoshi Kono
Makoto Nakamura
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Ryo Hashimoto
Tetsuya Kazama

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