Title:
NEW FORMULATION FOR INHALATION HAVING BULK DENSITY OF 0.28 TO 0.38 G/ML, PROCESS FOR PREPARING THE FORMULATION AND USE THEREOF
Document Type and Number:
Japanese Patent JP2010059181
Kind Code:
A
Abstract:
To provide an improved formulation which, in systems to imitate inhalation, achieves an improved dispersion of the drug.
A dry powder composition has a poured bulk density of 0.28-0.38 g/ml and includes one or more potent pharmaceutically active substances and a carrier substance, all of which are in finely divided form. The potent pharmaceutically active substance preferably includes budesonide and formoterol and the carrier substance includes lactose. This composition is useful in the treatment of respiratory disorders, particularly asthma.
Inventors:
TROFAST JAN
Application Number:
JP2009255070A
Publication Date:
March 18, 2010
Filing Date:
November 06, 2009
Export Citation:
Assignee:
ASTRAZENECA AB
International Classes:
A61K9/14; A61K9/00; A61K9/72; A61K31/137; A61K31/165; A61K31/167; A61K31/36; A61K31/58; A61K45/06; A61P11/00; A61P11/06; C07C233/24; C07J5/00; A61K
Domestic Patent References:
| JPS5859914A | 1983-04-09 |
Foreign References:
| WO1995009615A1 | 1995-04-13 | |||
| WO1995005805A1 | 1995-03-02 |
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Masayuki Nakagawa
Yasushi Ochiai
Takuji Yamada
Mitsutaka Iwasaki
Masayuki Nakagawa
Yasushi Ochiai
Previous Patent: NEW FORMULATION FOR INHALATION HAVING BULK DENSITY OF 0.28 TO 0.38 G/ML, COMPRISING FORMOTEROL
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