Title:
新規な高親和性のチオフェンベースおよびフランベースのキナーゼリガンド
Document Type and Number:
Japanese Patent JP2009504756
Kind Code:
A
Abstract:
Inhibitors of cyclin dependent kinase 2, compositions including the inhibitors, and methods of using the inhibitors and inhibitor compositions are described. The inhibitors and compositions including them are useful for treating disease or disease symptoms. The invention also provides for methods of making CDK-2 inhibitor compounds, methods of inhibiting CDK-2, and methods for treating disease or disease symptoms.
Inventors:
Den, Yonki
Chao, Lien Yun
Ships, Gerard W. Jr.
Karan, Patrick Jay.
Sidiki, M. Ashad
Chan, Lumin
McNemar, Charles W.
May Hood, Todd W.
Windsor, William Tee.
Reese, Emma.
Parry, David A.
Chao, Lien Yun
Ships, Gerard W. Jr.
Karan, Patrick Jay.
Sidiki, M. Ashad
Chan, Lumin
McNemar, Charles W.
May Hood, Todd W.
Windsor, William Tee.
Reese, Emma.
Parry, David A.
Application Number:
JP2008527100A
Publication Date:
February 05, 2009
Filing Date:
August 16, 2006
Export Citation:
Assignee:
Schering Corporation
International Classes:
C07D333/40; A61K31/381; A61K31/41; A61K31/4155; A61K31/416; A61K31/4178; A61K31/4196; A61K31/422; A61K31/427; A61K31/428; A61K31/433; A61K31/4439; A61K31/4535; A61K31/454; A61K31/4709; A61K31/4725; A61K31/496; A61K31/497; A61K31/498; A61K31/5377; A61K45/00; A61P1/18; A61P3/10; A61P7/12; A61P9/00; A61P11/00; A61P11/06; A61P25/16; A61P25/28; A61P29/00; A61P35/00; A61P35/02; A61P37/08; A61P43/00; C07D405/12; C07D405/14; C07D409/12; C07D409/14; C07D413/12; C07D413/14; C07D417/12; C07D417/14; C12N9/99
Domestic Patent References:
| JP2004534046A | 2004-11-11 | |||
| JPH04500664A | 1992-02-06 | |||
| JP2003500385A | 2003-01-07 | |||
| JP2004509857A | 2004-04-02 | |||
| JP2004501146A | 2004-01-15 | |||
| JP2006528962A | 2006-12-28 |
Foreign References:
| US3546255A | 1970-12-08 | |||
| EP0915088A1 | 1999-05-12 | |||
| GB1147295A | 1969-04-02 | |||
| WO2004069803A2 | 2004-08-19 | |||
| CN1131283A | 1996-09-18 | |||
| CH437347A | 1967-06-15 |
Other References:
MNDZHOYAN, A. L., ET AL.: ""Furan derivatives. XXXIX. Amides and amines of the furan-2,5-dicarboxylic acid series"", ARMYANSKII KHIMICHESKII ZHURNAL, vol. 22, no. 10, JPN6011012484, 1969, pages 933 - 935, ISSN: 0001869507
VOEGTLE, F., ET AL.: ""Amide-Based Rotaxanes with Terephthal, Fran, Thiophene and Sulfonamide Subunits"", SYNTHESIS, vol. 3, JPN6011012485, 1996, pages 353 - 356, ISSN: 0001869508
VOEGTLE, F., ET AL.: ""Amide-Based Rotaxanes with Terephthal, Fran, Thiophene and Sulfonamide Subunits"", SYNTHESIS, vol. 3, JPN6011012485, 1996, pages 353 - 356, ISSN: 0001869508
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita