NEW LINEAR OR CYCLIC UREA, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

Title:

NEW LINEAR OR CYCLIC UREA, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

Document Type and Number:

Japanese Patent JP3942935

Kind Code:

B2

Abstract:

PROBLEM TO BE SOLVED: To provide a medicine useful for the treatment of a disease or a pathological state which is known that the disorder of endothelial function is the cause of the disease and/or the mechanism of worsening the disease because the medicine can limit the disorder of the endothelial function or the reduction of ability for utilizing the blood vessel.
SOLUTION: The compound represented by formula (I) [wherein, V is a single bond or the like; M is a single bond or the like; A and E are each a nitrogen atom or the like; R3 is an aryl or a heteroaryl A group which may be substituted as necessary; Y is an aryloxy which may be substituted as necessary or the like], the isomer, the hydrate, the solvate or the addition salt with a pharmaceutically acceptable acid are provided. The pharmaceutical composition containing the compound is also provided.

Inventors:

Jean-Louis Perillon
Christoph Pwatovan
Jean-Paul Vilan
Nicole Villeneuve
Marie-Pierre Bourguignon
Catherine Tron

Application Number:

JP2002106212A

Publication Date:

July 11, 2007

Filing Date:

December 27, 2000

Export Citation:

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Assignee:

Réra Bora Toir Servier

International Classes:

C07D401/06; C07D417/14; A61K31/437; A61K31/4427; A61K31/443; A61K31/4439; A61K31/454; A61K31/4545; A61K31/4709; A61K31/4725; A61K31/496; A61K31/497; A61K31/506; A61K31/513; A61K31/551; A61P3/06; A61P3/10; A61P9/00; A61P9/08; A61P9/10; A61P9/12; A61P43/00; C07D209/08; C07D211/26; C07D211/58; C07D401/12; C07D403/06; C07D405/06; C07D405/12; C07D405/14; C07D413/12; C07D417/06; C07D471/04; C07D491/04; A61K31/00; C07D211/00; (IPC1-7): C07D401/06; A61K31/437; A61K31/4439; A61K31/454; A61K31/4545; A61K31/4709; A61K31/4725; A61K31/496; A61K31/506; A61K31/551; A61P3/06; A61P3/10; A61P9/10; A61P9/12; C07D401/12; C07D403/06; C07D405/14; C07D417/06; C07D471/04

Domestic Patent References:

JP54157570A
JP52105182A
JP51113878A

Foreign References:

WO1997028157A1

Attorney, Agent or Firm:

Hajime Tsukuni
Fumio Shinoda

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