Title:
高純度プロスタグランジンの新規製造方法
Document Type and Number:
Japanese Patent JP6659563
Kind Code:
B2
Abstract:
The subject of the invention is a process for the preparation of high purity prostaglandin acid of the general formula II wherein the bonds marked with dotted lines represent single or double bonds wherein the double bonds may be cis- or trans oriented, Y represents 0 or CH 2, and R3 stands for a phenyl group which is optionally substituted with CF3, wherein the crude prostaglandin acid of the general formula II is purified by normal phase silicagel chromatography.
Inventors:
Erwin Weida
Iren Holtberg
Istban Raszolofi
Peter Boozerlands
Garbol Havashy
Lazlo Takach
Giuganna Cardos
Iren Holtberg
Istban Raszolofi
Peter Boozerlands
Garbol Havashy
Lazlo Takach
Giuganna Cardos
Application Number:
JP2016556930A
Publication Date:
March 04, 2020
Filing Date:
March 11, 2015
Export Citation:
Assignee:
Kinoin Jiojicel Aceille Bezier Sete Thermekek Jyara See El Te
International Classes:
C07C405/00; B01J20/283; G01N30/26; G01N30/88
Domestic Patent References:
| JP2003520848A | ||||
| JP2012530783A | ||||
| JP1221331A | ||||
| JP2005503354A | ||||
| JP3501025A |
Foreign References:
| WO2013186550A1 | ||||
| WO2012164324A1 | ||||
| US20080207926 | ||||
| WO2013093528A1 |
Other References:
J. Med. Chem. ,2000年,43,945-952
Tetrahedron,2010年,66,7472-7478
Tetrahedron,2010年,66,7472-7478
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Noriyuki Takebayashi