Title:
NEW MICROORGANISM AND PRODUCTION OF L-ASPARTIC ACID, FUMARIC ACID AND/OR L-MALIC ACID
Document Type and Number:
Japanese Patent JP3165040
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To produce fumaric acid and/or L-malic acid over a long period without exchanging microorganisms by treating maleic acid with microbial cells of a specific microorganism, the treated cells or their immobilized product.
SOLUTION: Maleic acid is treated with cells of Pseudomonas alcaligenes XD-1 strain (FERM P-15715),the treated cells or their immobilized product. The maleic acid isomerase of the above microorganism, etc., has long half-life period of the activity and the enzymatic activity is not lowered in a short time. L-aspartic acid can be produced by treating maleic acid and ammonia with the above microorganism (including the treated cells or their immobilized product) and a microorganism capable of producing aspartase (including the treated cells or their immtobilized product).
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Inventors:
Tadaatsu Nakahara
Toshiaki Kobe
Masaharu Mukaiyama
Kouichi Sakano
Toshiaki Kobe
Masaharu Mukaiyama
Kouichi Sakano
Application Number:
JP23190196A
Publication Date:
May 14, 2001
Filing Date:
September 02, 1996
Export Citation:
Assignee:
Nippon Shokubai Co., Ltd.
International Classes:
C12P7/46; C12N1/20; C12P13/20; C12R1/38; (IPC1-7): C12N1/20; C12P7/46; C12P13/20
Domestic Patent References:
| JP851991A | ||||
| JP4211993B1 | ||||
| JP4211994B1 |
Other References:
Ａｇｒｉｃ．Ｂｉｏｌ．Ｃｈｅｍ．，５０（１），８９−９４（１９８６）
Attorney, Agent or Firm:
Yusuke Hiraki (1 person outside)
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