Title:
新規ヌクレアーゼドメインおよびその利用
Document Type and Number:
Japanese Patent JP6892721
Kind Code:
B2
Abstract:
The present invention provides an artificial nucleic acid-cleaving enzyme comprising: a nuclease domain which is a polypeptide containing an amino acid sequence set forth at positions 391 to 585 of SEQ ID NO: 1 or positions 389 to 579 of SEQ ID NO: 3, or a mutant polypeptide thereof; and a nucleic acid-binding domain.
Inventors:
Taku Yamamoto
Sakuma Satoshi
Katsukazu Saito
Sakuma Satoshi
Katsukazu Saito
Application Number:
JP2020539416A
Publication Date:
June 23, 2021
Filing Date:
August 23, 2019
Export Citation:
Assignee:
Hiroshima University
International Classes:
C12N15/09; C07K19/00; C12N9/16; C12N15/31; C12N15/55; C12N15/62; C12N15/63
Foreign References:
| WO2014175284A1 | ||||
| WO2012168304A1 |
Other References:
Database GenBank [online], Accession No.KSU87972.1,04-Dec-2015,[retrieved on 30.09.2019],URL,http://www.ncbi.nlm.nih.gov/protein/KSU87972
Database GenBank [online], Accession No.LNQP01000031.1,04-DEC-2015, [retrieved on 30.09.2019],URL,http://www.ncbi.nlm.nih.gov/nuccore/LNQP01000031.1
Database GenBank [online], Accession No.MZGW01000003.1,15-MAR-2017, [retrieved on 30.09.2019],URL,http://ncbi.nlm.nih.gov/nuccore/MZGW01000003.1
Molecular Therapy (2009) Vol.17, No.1, pp.104-111
Database GenBank [online], Accession No.LNQP01000031.1,04-DEC-2015, [retrieved on 30.09.2019],URL,http://www.ncbi.nlm.nih.gov/nuccore/LNQP01000031.1
Database GenBank [online], Accession No.MZGW01000003.1,15-MAR-2017, [retrieved on 30.09.2019],URL,http://ncbi.nlm.nih.gov/nuccore/MZGW01000003.1
Molecular Therapy (2009) Vol.17, No.1, pp.104-111
Attorney, Agent or Firm:
Patent Business Corporation St. Crest International Patent Office