Title:
NEW POLYPEPTIDE AND NUCLEIC ACID ENCODING THE SAME
Document Type and Number:
Japanese Patent JP2006206587
Kind Code:
A
Abstract:
To provide a new polypeptide homologous to A33 antigen and HCAR membrane-binding protein.
The new polypeptide has a specific amino acid sequence named as PRO362, or has an amino acid sequence where one or several amino acids are deleted, substituted or added in the above amino acid sequence, having anti-tumor proliferation activity. This polypeptide is usable as a drug for treating tumors, being also usable as a means for detecting the presence of a tumor in a biological specimen. Besides, this polypeptide enables a humanized monoclonal antibody to the above-mentioned protein to be obtained.
Inventors:
WOOD WILLIAM I
GODDARD AUDREY
GURNEY AUSTIN
YUAN JEAN
BAKER KEVIN P
CHEN JIAN
GODDARD AUDREY
GURNEY AUSTIN
YUAN JEAN
BAKER KEVIN P
CHEN JIAN
Application Number:
JP2006010705A
Publication Date:
August 10, 2006
Filing Date:
January 19, 2006
Export Citation:
Assignee:
GENENTECH INC
International Classes:
C07K14/47; C12N15/09; A61K31/7088; A61K35/76; A61K38/00; A61K38/17; A61K39/395; A61K45/00; A61K48/00; A61P7/02; A61P9/00; A61P19/08; A61P25/02; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P35/00; A61P43/00; C07K14/705; C07K16/18; C07K16/28; C07K16/30; C07K16/40; C07K16/46; C07K19/00; C12N1/19; C12N1/21; C12N5/10; C12N9/00; C12N9/04; C12N9/64; C12N15/63; C12P21/02; C12P21/08; C12Q1/02; C12Q1/68; G01N33/50; G01N33/53; G01N33/566; G01N33/574; G01N33/68; C12R1/19; C12R1/91
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori