Title:
NEW PRODUCTION METHOD OF 14 ALPHA-HYDROXY-4-ANDROSTENE-3, 6,17-TRIONE
Document Type and Number:
Japanese Patent JPH08176187
Kind Code:
A
Abstract:
PURPOSE: To newly obtain 14α-hydroxy-4-androstene-3,6,17-trione useful as an anti-cancer medicine.
CONSTITUTION: 14α-Hydroxy-4-androstene-3,6,17-trione is obtained by oxidizing a hydroxyl group at 6-position of 6,14α-dihydroxy-4-androstene-3,17-dione using an N-halogenoimide or N-halogenoamide as an oxidizer in the presence of light or a polymerization initiator. The process gives a high yield and a high processability and the resultant 14α-hydroxy-4-androstene-3,6,17-trione is safe because any heavy metal is not used in the process.
Inventors:
IMAIZUMI YOSHIHIRO
MITSUNOBU SHIYOUICHI
MITSUNOBU SHIYOUICHI
Application Number:
JP33695094A
Publication Date:
July 09, 1996
Filing Date:
December 27, 1994
Export Citation:
Assignee:
NIPPON KAYAKU KK
International Classes:
A61K31/565; A61P35/00; C07J1/00; C07J75/00; (IPC1-7): C07J75/00; A61K31/565; C07J1/00