Title:
新規なピリジニルアミノアルキレン-およびピリジニルオキシアルキレン-シクロプロパンアミン類、それらの製造方法ならびにそれらを含有する医薬組成物
Document Type and Number:
Japanese Patent JP2009525311
Kind Code:
A
Abstract:
Compounds of formula (I): wherein: n represents an integer of from 1 to 6 inclusive, X represents an oxygen atom or an NR6 group, Y represents a carbon atom or a nitrogen atom, Z represents a carbon atom or a nitrogen atom, R1 and R2 represent a hydrogen atom or an alkyl or arylalkyl group, R3 and R4 represent a hydrogen atom or an alkyl group, R5 represents a hydrogen atom or an alkyl, halogen, hydroxy, alkoxy, cyano, nitro, acyl, alkoxycarbonyl, trihaloalkyl, trihaloalkoxy or optionally substituted amino group, R6 represents a hydrogen atom or an alkyl or arylalkyl group, Ra, Rb, Rc, Rd and Re are as defined in the description. Medicinal products containing the same which are useful as specific nicotinic ligands of α4β2 receptors.
Inventors:
Gold stan, solo
Gironnow, Claude
Shalton, eve
Rocker, brian
Lestage, Pierre
Gironnow, Claude
Shalton, eve
Rocker, brian
Lestage, Pierre
Application Number:
JP2008552845A
Publication Date:
July 09, 2009
Filing Date:
January 30, 2007
Export Citation:
Assignee:
Réra Bora Toir Servier
International Classes:
C07D213/65; A61K31/4418; A61K31/4439; A61K31/444; A61P25/00; A61P25/02; A61P25/14; A61P25/16; A61P25/18; A61P25/28; A61P25/34; A61P29/00; A61P43/00; C07D213/74; C07D401/10; C07B61/00
Attorney, Agent or Firm:
Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito
Koshiro Tsukuda
Fusayuki Saito