NEW MATERIAL: A compound of formula I [E and G are formula II (or formula III of tautomer of the same), formula IV or formula V (R is H, alkyl, alkenyl, or alkinyl; Y is carbocyclic, complex monocyclic or condensation heterocyclic aryl) together, or E is CO2R3 (R3 is H or an alkyl), and G is CRH-Y; A is a cycloalkyl of 3-6C, CBH-CH2 (B is an aryl, cycloalkyl, alkyl or the like); R1 and R2 are each an alkyl, alkenyl, alkinyl or 5-7 membered heterocycle with N to be combined].
EXAMPLE: (1S)-3-(3,4-dichlorophenyl)-1-[1-phenyl-2-(1-pyrrolidinyl)ethyl]-2- piperidinone.
USE: Analgesics and medicines for arrhythmia.
PROCESS: For example, amine of formula VI and acrylic ester of formula VII are used as the starting materials, to obtain the compound of formula I.
MISHIERU FUORUTAN
ODEIRU RU MARUTORE
