Title:
NEW SAPONIN COMPOUND AND DESACYL SAPONIN COMPOUND
Document Type and Number:
Japanese Patent JP3441488
Kind Code:
B2
Abstract:
PURPOSE: To provide a new saponin compound and desacyl saponin compound, having anti-inflammatory and anti-allergic activity, useful as a medicine.
CONSTITUTION: The objective saponin compound of formula I (teasaponin B1) and desacyl tea saponin B of formula II. The teasaponin B1 of the formula I can be obtained by the following process: raw or steamed tea leaves or tea leaves processed for drinking use are subjected to extraction with a (hydrous) lower aliphatic alcohol and the resultant extract is put to one of various kinds of chromatography followed by separation and purification using high- performance liquid chromatography. The other objective desacyl teasaponin B of the formula II can be obtained by hydrolyzing the compound of the formula I.
Inventors:
Isao Kitagawa
Sukemasa Kobayashi
Hiroko Sasaka
Uemura Terumi
Sukemasa Kobayashi
Hiroko Sasaka
Uemura Terumi
Application Number:
JP20975193A
Publication Date:
September 02, 2003
Filing Date:
August 24, 1993
Export Citation:
Assignee:
ITO EN Co., Ltd.
International Classes:
A61K31/70; A61K31/7028; A61K31/7034; A61K31/704; A61P29/00; A61P37/08; C07H15/256; C07J63/00; (IPC1-7): C07J63/00
Other References:
Ｃｈｅｍ．Ｐｈａｒｍ．Ｂｕｌｌ．，１９８０年，Ｖｏｌ．２８，Ｎｏ．１−，ｐ．２９６−３００
薬学雑誌，１９９２年，Ｖｏｌ．１１２，Ｎｏ．１，ｐ．１−４１
薬学雑誌，１９９２年，Ｖｏｌ．１１２，Ｎｏ．１，ｐ．１−４１
Attorney, Agent or Firm:
Masataka Oshima
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