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Title:
NEW SULFATE DERIVATIVE OF GALACTAN EXTRACTED FROM GENUS KLEBSIELLA, ITS PRODUCTION, ITS USE AS MEDICINE AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE
Document Type and Number:
Japanese Patent JPH04108801
Kind Code:
A
Abstract:

NEW MATERIAL: A sulfate deriv. of galactan extracted from the genus Klebsiella mainly composed of neutral carbohydrate sulfated in a ratio of hydroxyl 20-90%.

USE: An immunostimulation agent, an anti-erastase agent and an anticoagulant.

PROCESS: Acylglucan mainly consisting of about 80% of neutral carbohydrate, 20% of lipid and below 2% of protein and having a mol.wt. of 12500 and extracted from the genus Klebsiella is treated with mild acid hydroysis to be applied to high performance chromatography using a negative ion exchanger to collect a non-held fraction which is, in turn, filtered on a gel to collect a fraction containing galactan having a mol.wt. of 4000-10000 and this obtd. galactan fraction is sulfated and purified by dialysis to be isolated.


Inventors:
PIEERU SUMETSU
RUNE ZARISU
Application Number:
JP40342390A
Publication Date:
April 09, 1992
Filing Date:
December 03, 1990
Export Citation:
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Assignee:
ROUSSEL UCLAF
International Classes:
A61K31/715; A61P37/00; A61P37/08; C08B37/00; C12P19/04; (IPC1-7): A61K31/715; C08B37/00
Attorney, Agent or Firm:
Motohiro Kurauchi (1 outside)



 
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