Title:
新規テクネチウム及びレニウム錯体
Document Type and Number:
Japanese Patent JP5122964
Kind Code:
B2
Abstract:
Novel radioactive technetium and rhenium complexes comprising tripodal ligands are provided by the present invention. In particular, Tc(I) complexes are provided by the present invention. Novel ligands suitable for the formation of the technetium and rhenium complexes of the invention are also provided, as well as radiopharmaceutical compositions comprising said complexes, kits for their preparation. The invention also relates to the use of 99mTc radiopharmaceuticals of the invention for SPECT imaging.
More Like This:
Inventors:
Barra, Rajib
Application Number:
JP2007534091A
Publication Date:
January 16, 2013
Filing Date:
October 04, 2005
Export Citation:
Assignee:
GE HEALTHCARE LIMITED
International Classes:
C07D213/40; C07D213/56; C07D213/81; C07D213/82; C07D401/14; C07F13/00
Domestic Patent References:
| JP10045903A |
Foreign References:
| WO2003077727A1 |
Other References:
Reger, Daniel L.,Rhenium tricarbonyl complexes of tris(pyrazolyl)methane ligands: first structural characterization of an isomer pair of tris(pyrazolyl)methane derivatives and the supramolecular structure of the homobimetallic complex {1,4-C6H4[CH2OCH2C(pz)3]2[Re(CO)3]2}(Br)2,Journal of Organometallic Chemistry,2002年,658(1-2),p. 50-61
Hannon, Michael J.,Synthesis and characterisation of water-soluble poly(aryl ether) dendrimers for encapsulation of biomimetic active site analogues,Perkin 1,2000年,(12),p. 1881-1889
ARNOLD P J,JOURNAL OF THE CHEMICAL SOCIETY. DALTON TRANSACTIONS,2001年 3月 7日,N5,P736-746
Schibli, Roger,Steps toward High Specific Activity Labeling of Biomolecules for Therapeutic Application: Preparation of Precursor [188Re(H2O)3(CO)3]+ and Synthesis of Tailor-Made Bifunctional Ligand Systems,Bioconjugate Chemistry,2002年,13(4),p. 750-756
Gerber, T. I. A.,Nucleophilic addition of water and ethanol to coordinated di-(2-pyridyl)ketone in rhenium(V) and technetium(V) complexes. The crystal structure of dichloro(hydroxy-di-(2-pyridyl)methoxide)oxorhenium(V),Journal of Coordination Chemistry,1993年,28(3-4),p. 329-336
Hannon, Michael J.,Synthesis and characterisation of water-soluble poly(aryl ether) dendrimers for encapsulation of biomimetic active site analogues,Perkin 1,2000年,(12),p. 1881-1889
ARNOLD P J,JOURNAL OF THE CHEMICAL SOCIETY. DALTON TRANSACTIONS,2001年 3月 7日,N5,P736-746
Schibli, Roger,Steps toward High Specific Activity Labeling of Biomolecules for Therapeutic Application: Preparation of Precursor [188Re(H2O)3(CO)3]+ and Synthesis of Tailor-Made Bifunctional Ligand Systems,Bioconjugate Chemistry,2002年,13(4),p. 750-756
Gerber, T. I. A.,Nucleophilic addition of water and ethanol to coordinated di-(2-pyridyl)ketone in rhenium(V) and technetium(V) complexes. The crystal structure of dichloro(hydroxy-di-(2-pyridyl)methoxide)oxorhenium(V),Journal of Coordination Chemistry,1993年,28(3-4),p. 329-336
Attorney, Agent or Firm:
Arakawa Satoshi
Hirokazu Ogura
Toshihisa Kurokawa
Hirokazu Ogura
Toshihisa Kurokawa