Title:
New therapeutic RNA interference art which makes a target PDX-1 oncogene in a PDX-1 revelation neuroendocrine tumor
Document Type and Number:
Japanese Patent JP6007103
Kind Code:
B2
Abstract:
A bifunctional shRNA-based composition and methods for knocking down the expression of the PDX-1 oncogene in target cells is described herein. The invention also provides methods to deliver the shRNA-containing expression vectors to target tissues overexpressing the PDX-1 oncogene.
Inventors:
Nem Nightis John Jay.
Lao Donald
Bruni Cardiff. Charles
Lao Donald
Bruni Cardiff. Charles
Application Number:
JP2012537017A
Publication Date:
October 12, 2016
Filing Date:
October 27, 2010
Export Citation:
Assignee:
STRIKE BIO,INC.
BAYLOR COLLEGE OF MEDICINE
BAYLOR COLLEGE OF MEDICINE
International Classes:
C12N15/113; A61K9/127; A61K9/14; A61K31/7105; A61K47/30; A61K47/42; A61K48/00; A61P1/18; A61P35/00
Domestic Patent References:
| JP2003534811A | ||||
| JP2006513191A |
Foreign References:
| US20080269474 |
Other References:
Pancreas,2008,Vol.37,No.2,p.210-220
Attorney, Agent or Firm:
Masaki Hirota
Seiji Ozawa
Yusaku Tokai
Makoto Horiuchi
Masako Yamauchi
Shuichi Sonomoto
Seiji Ozawa
Yusaku Tokai
Makoto Horiuchi
Masako Yamauchi
Shuichi Sonomoto
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