Title:
新規トロンビン機能性化合物およびそれらに基づいた医薬組成物
Document Type and Number:
Japanese Patent JP2010531352
Kind Code:
A
Abstract:
This invention relates to new chemical compounds, application of these compound as thrombin inhibitors, and pharmaceutical compositions based on them, and can be used to treat and prevent thrombin-dependent thromboembolic events, and in research.
Inventors:
Sinaurize, Elena Ivanovna
Ataulak Khanov, Fazoil Inoyatovic
Butyrin, Andrei Alexandrovich
Srimov, Vladimir Borisovic
Romanov, Alexei Nikolaivic
Bogolyubov, Alexei Alexevich
Kuznetsov, Yury Vladimirovich
Grykhkova, Irina Vladimir Khovna
Gobatenko, Alexander Saggy Vitch
Condakova, Olga Anatolyfna
Ataulak Khanov, Fazoil Inoyatovic
Butyrin, Andrei Alexandrovich
Srimov, Vladimir Borisovic
Romanov, Alexei Nikolaivic
Bogolyubov, Alexei Alexevich
Kuznetsov, Yury Vladimirovich
Grykhkova, Irina Vladimir Khovna
Gobatenko, Alexander Saggy Vitch
Condakova, Olga Anatolyfna
Application Number:
JP2010514671A
Publication Date:
September 24, 2010
Filing Date:
June 27, 2008
Export Citation:
Assignee:
Obstosvo S Ogranichenoi Otovetostvenostu "Bionika"
International Classes:
C07C335/32; A61K31/155; A61K31/4425; A61K31/443; A61K31/4436; A61K31/4439; A61K31/444; A61K31/4545; A61K31/497; A61K31/501; A61K31/505; A61K31/506; A61P7/02; A61P9/10; A61P43/00; C07D213/73; C07D239/42; C07D405/12; C07D409/12; C07D413/12; C07D417/12
Domestic Patent References:
| JP2005126428A | 2005-05-19 | |||
| JPH08509723A | 1996-10-15 | |||
| JP2009538931A | 2009-11-12 | |||
| JP2010531353A | 2010-09-24 | |||
| JPH0341065A | 1991-02-21 | |||
| JPH08507503A | 1996-08-13 | |||
| JPH10504833A | 1998-05-12 | |||
| JP2001500864A | 2001-01-23 | |||
| JP2000507588A | 2000-06-20 | |||
| JPH05134337A | 1993-05-28 |
Foreign References:
| WO2005094828A1 | 2005-10-13 | |||
| US5089634A | 1992-02-18 | |||
| US20050159457A1 | 2005-07-21 | |||
| US5886191A | 1999-03-23 | |||
| US3407229A | 1968-10-22 |
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JOURNAL OF ORGANIC CHEMISTRY, vol. 26, JPN6013029560, 1961, pages 2740 - 7, ISSN: 0002558596
Attorney, Agent or Firm:
Eijiro Tanikawa