Title:
デングウイルスの複数のサブタイプに対する新規ワクチン
Document Type and Number:
Japanese Patent JP5788676
Kind Code:
B2
Abstract:
An aspect of the present invention is related to nucleic acid constructs capable of expressing a polypeptide that elicits an immune response in a mammal against more than one subtype of dengue virus, and methods of use thereof. Additionally, there are DNA plasmid vaccines capable of generating in a mammal an immune response against a plurality of dengue virus subtypes, comprising a DNA plasmid and a pharmaceutically acceptable excipient, and methods of use thereof. The DNA plasmid is capable of expressing a consensus dengue antigen in a cell of the mammal in a quantity effective to elicit an immune response in the mammal.
Inventors:
Ramanathan, Masrapee.
Sardesai, Niranjan Wai.
Sardesai, Niranjan Wai.
Application Number:
JP2010542412A
Publication Date:
October 07, 2015
Filing Date:
January 12, 2009
Export Citation:
Assignee:
Inobio Pharmaceuticals, Incorporated
International Classes:
C12N15/09; A61K39/12; A61K48/00; A61P31/16; A61P31/18; A61P31/20
Other References:
Vaccine,2005年,Vol.23,p.3469-3476
DNA AND CELL BIOLOGY,2007年,Vol.26,p.361-367
Am.J.Trop.Med.Hyg.,2006年,Vol.74,p.266-277
DNA AND CELL BIOLOGY,2007年,Vol.26,p.361-367
Am.J.Trop.Med.Hyg.,2006年,Vol.74,p.266-277
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei