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Patent Searching and Data


Title:
NIFEDIPINE-CONTAINING PLASTER
Document Type and Number:
Japanese Patent JPS6118717
Kind Code:
A
Abstract:

PURPOSE: The titled plaster that is obtained by forming the cataplasm base layer containing active ingredients, which has been prepared by dissolving nifedipine, an antistenocardic, in a specific solvent and dispersing the solution in a base material, on a support coated with a tackifier, thus showing good percutaneous absorption of the active ingredients without rash.

CONSTITUTION: For example, nifedipine is dissolved in isopropyl myristate (abbreviated to IPM) and/or isopropyl lanolate (abbreviated to IPL) and the solution is dispersed in a cataplasm base material. The support 1 coated with a tackifier 2 is laminated with the resultant plasta base layer containing nifedipine to give the objective plaster. The horny layer is softened by the moisture in the base layer and the permeability of nifedipine is increased by use of IPM and IPL, resulting in effective percutaneous absorption of nifedipine. Further, the area in which the tackifier contacts with skins decreases rash.


Inventors:
ITOU TOSHIO
Application Number:
JP13798584A
Publication Date:
January 27, 1986
Filing Date:
July 05, 1984
Export Citation:
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Assignee:
NICHIBAN KK
International Classes:
C07D211/90; A61K9/70; A61K31/44; (IPC1-7): A61K9/70; A61K31/44; C07D211/90
Attorney, Agent or Firm:
Masao Isaka