Title:
生分解性の抗菌性足場としての一酸化窒素放出性アルギン酸塩およびそれに関する方法
Document Type and Number:
Japanese Patent JP7366406
Kind Code:
B2
Abstract:
Large molecular weight alginates which are covalently modified to store and release nitric oxide, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates may be tailored to release nitric oxide in a controlled manner and are useful for eradication of both planktonic and biofilm-based bacteria.
Inventors:
Schoenfisch, Mark H.
Ahonen, Mona Jasmine Earl.
Suchita, Dakota Jay.
Rouillard, Caitlin Rose
Ahonen, Mona Jasmine Earl.
Suchita, Dakota Jay.
Rouillard, Caitlin Rose
Application Number:
JP2019556425A
Publication Date:
October 23, 2023
Filing Date:
January 03, 2018
Export Citation:
Assignee:
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
International Classes:
C08B37/04; A61K31/165; A61K31/43; A61K31/545; A61K31/546; A61K31/65; A61K31/7048; A61K31/7052; A61K31/7056; A61K31/734; A61K33/00; A61L29/08; A61L29/14; A61L29/16; A61L31/10; A61L31/14; A61L31/16; A61P1/00; A61P1/16; A61P7/02; A61P9/00; A61P11/00; A61P15/00; A61P17/02; A61P25/04; A61P29/00; A61P31/00; A61P31/04; A61P31/06; A61P31/10; A61P31/12; A61P31/14; A61P31/16; A61P31/18; A61P31/20; A61P31/22; A61P33/00; A61P35/00; A61P37/06; A61P43/00
Domestic Patent References:
| JP2015524877A |
Other References:
Drug Delivery,2015年12月15日,Vol.23(8),p.2927-2935
British Journal of Pharmacology,2007年04月02日,Vol.151,p.305-321
British Journal of Pharmacology,2007年04月02日,Vol.151,p.305-321
Attorney, Agent or Firm:
Takashi Shoji
Yuriko Sukenobu
Takuya Osugi
Hirata Midori
Yuriko Sukenobu
Takuya Osugi
Hirata Midori