含窒素5員複素環化合物

Japanese Patent JP4416994

B2

Use of a compound of the formula: wherein R<1> represents a hydrocarbon group which may be substituted or a heterocyclic group which may be substituted; X represents a bond, an oxygen atom, a sulfur atom, or a group of the formula: -CO-, -CS-, -CR<4>(OR<5>)- or -NR<6>- wherein each of R<4> and R<6> represents a hydrogen atom or a hydrocarbon group which may be substituted, R<5> represents a hydrogen atom or a protective group for a hydroxyl group; m represents an integer of 0 to 3; Y represents an oxygen atom, a sulfur atom, or a group of the formula: -SO-, -SO2-, -NR<7>-, -CONR<7>- or -NR<7>CO- wherein R<7> represents a hydrogen atom or a hydrocarbon group which may be substituted; ring A represents an aromatic ring which may further have 1 to 3 substituents; n represents an integer of 1 to 8; ring B represents a nitrogen-containing 5-membered hetero ring which may further be substituted by an alkyl group; X<1> represents a bond, an oxygen atom, a sulfur atom, or a group of the formula: -SO-, -SO2-, -O-SO2- or -NR<16>- wherein R<16> represents a hydrogen atom or a hydrocarbon group which may be substituted; R<2> represents a hydrogen atom, a hydrocarbon group which may be substituted or a heterocyclic group which may be substituted; W represents a bond or a divalent hydrocarbon residue having 1 to 20 carbon atoms; R<3> represents a group of the formula: -OR<8> (R<8> represents a hydrogen atom or a hydrocarbon group which may be substituted) or -NR<9>R<10> (each of R<9> and R<10>, whether identical or not, represents a hydrogen atom, a hydrocarbon group which may be substituted, a heterocyclic group which may be substituted, or an acyl group which may be substituted; R<9> and R<10> may bind together to form a ring); or a salt thereof, for the manufacture of a pharmaceutical preparation for preventing or treating syndrome X.

JPS5320492	NOVEL ANTIBIOTIC
JP4190285	5- (4-Fluorophenyl) -1- [2-((2R, 4R) -4-hydroxy-6-oxotetrahydropyran-2-yl) ethyl] -2-isopropyl-4-phenyl-1H-pyrrole- A novel method for synthesizing 3-carboxylic acid phenylamide
JP5412484	Salt form of atorvastatin

Yu Momose
Maekawa Takeshi
Hiroyuki Odaka
Hiroyuki Kimura

JP2002315096A

February 17, 2010

October 29, 2002

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Takeda GmbH

C07D207/34; C07D231/12; A61K31/40; A61K31/4025; A61K31/415; A61K31/4155; A61K31/4184; A61K31/4192; A61K31/422; A61K31/4245; A61K31/427; A61K31/437; A61K31/4427; A61K31/4439; A61K31/4545; A61K31/4709; A61K31/497; A61K31/501; A61K31/502; A61K31/5415; A61K45/00; A61P1/00; A61P1/02; A61P1/04; A61P1/12; A61P1/14; A61P1/16; A61P1/18; A61P3/00; A61P3/04; A61P3/06; A61P3/08; A61P3/10; A61P5/00; A61P5/24; A61P5/50; A61P7/00; A61P7/06; A61P7/10; A61P9/04; A61P9/08; A61P9/10; A61P9/12; A61P9/14; A61P11/00; A61P11/04; A61P13/02; A61P13/08; A61P13/10; A61P13/12; A61P15/00; A61P15/08; A61P15/10; A61P17/00; A61P19/00; A61P19/02; A61P19/06; A61P19/10; A61P21/00; A61P21/04; A61P25/00; A61P25/02; A61P25/04; A61P25/16; A61P25/28; A61P27/02; A61P27/12; A61P27/16; A61P29/00; A61P31/00; A61P31/06; A61P31/14; A61P31/18; A61P31/20; A61P35/00; A61P35/02; A61P37/02; A61P43/00; C07D207/325; C07D207/333; C07D207/337; C07D231/14; C07D401/04; C07D401/12; C07D401/14; C07D403/12; C07D405/12; C07D407/12; C07D409/12; C07D409/14; C07D413/12; C07D413/14; C07D417/12; C07D417/14; C07D471/04; C07D487/04; A61K; C07D409/00; A61P; C07D; C07D401/00; C07D405/00; C07D413/00; C07D417/00

JP3723071B2
JP11158175A
JP2000034266A
JP2001199887A

WO1998006720A1
WO2001045700A1

Takashima Ichi

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