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Title:
NOVEL 17 ALPHAAARYLSTEROID DERIVATIVE*ITS MANUFACTURE AND PHARMACEUTICAL COMPOSITION CONTAINING IT
Document Type and Number:
Japanese Patent JPS5473764
Kind Code:
A
Abstract:
Novel 17 alpha -aryl-steroids of the formula I wherein R1 is alkyl of 1 to 3 carbon atoms, R2 is selected from the group consisting of hydrogen, alkyl of 1 to 12 carbon atoms and acyl of an organic carboxylic acid of 1 to 18 carbon atoms, R3 is aryl of 6 to 12 carbon atoms optionally substituted with at least one substituent selected from the group consisting of -OH, halogen, alkoxy and alkyl of 1 to 4 carbon atoms and -CF3, the dotted line in the B ring indicating an optional double bond in the 9(10)-position, and A and B are hydrogen and when there is a double bond in the 9(10)-position, A and B form a double bond in the 11(12) position or B is hydrogen and A is an 11 beta -hydroxy having progestomimetic activity activity without androgenic activity and a process for their preparation and novel intermediates produced therein.

Inventors:
JIYUNUBIEEBU AZADEIAN
DANIERU FUIRIBEERU
ANDORE PIERUDE
Application Number:
JP13684378A
Publication Date:
June 13, 1979
Filing Date:
November 08, 1978
Export Citation:
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Assignee:
ROUSSEL UCLAF
International Classes:
A61K31/565; C07J1/00; C07J21/00; (IPC1-7): A61K31/565; C07J1/00