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Title:
NOVEL 4-HOMOISOTWISTANAMIDE DERIVATIVE
Document Type and Number:
Japanese Patent JPS5583740
Kind Code:
A
Abstract:

NEW MATERIAL:A compound of formula I (R1,2 are halogen, lower alkyl, lower alkoxy, lower acyl, or nitro; a is 0 or 1; b is 0 or 1; c and d are 0 or 1W5 provided that c+d≤5).

EXAMPLE: N-[3-(4-Homoisotwistyl)]-4-methylbenzamide.

USE: A remedy for viral diseases of man and animals, effective to DNA viruses (esp. herpes virus) as well as DNA viruses, and inactive to central nervous system.

PROCESS: Reaction of 4-homoisotwistanamine II with an acid halide III (X is halogen) in an inert organic solvent in the presence of a basic catalyst affords the compound I.


Inventors:
INAMOTO YOSHIAKI
OOSUGI MOTOYOSHI
KASHIHARA EIJI
Application Number:
JP15821578A
Publication Date:
June 24, 1980
Filing Date:
December 18, 1978
Export Citation:
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Assignee:
KAO CORP
SUMITOMO CHEMICAL CO
International Classes:
A61K31/165; A61P31/12; C07C67/00; C07C231/00; C07C233/11; C07C233/65; C07C235/34; C07C235/36; C07C235/46; C07C235/54; C07C235/78; C07C235/84; (IPC1-7): A61K31/165; C07C103/76