NOVEL 5-SUBSTITUTED 2-PYRIMIDINONENUCLEOSIDES AND USE

Title:

NOVEL 5-SUBSTITUTED 2-PYRIMIDINONENUCLEOSIDES AND USE

Document Type and Number:

Japanese Patent JPS6153296

Kind Code:

A

Abstract:

Compounds for inhibiting the replication of DNA viruses which induce the formation of thymidine kinase enzyme of the formula: wherein R1 is a radical selected from the group consisting of chloro, iodo, hydroxy, alkoxyalkyl, hydroxyalkyl, methylamino, formyl, nitro, and unsubstituted hydrocarbon groups of 2 to about 3 carbon atoms or halosubstituted hydrocarbon groups of 1 to about 3 carbon atoms; R2 is hydrogen or hydroxy; and R3 is hydroxy, -OP(O)(OH)2, amino, or -OCOR4 where R4 is alkyl or alkoxyalkyl of 2 to about 18 carbon atoms.

Inventors:

TOOMASU JIYOSEFU BAADOSU
YUN CHI CHIEN
ARAN KAATEISU SHIYUROODAA
SAIMON MUBUA NAGEIRU EFUANGE

Application Number:

JP17819584A

Publication Date:

March 17, 1986

Filing Date:

August 27, 1984

Export Citation:

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Assignee:

UNIV NEW YORK

International Classes:

C07H19/067; A61K31/70; A61K31/7042; A61K31/7052; A61K31/7064; A61P31/12; C07D239/34; C07D239/36; C07H19/06; C07H19/073; C07H19/16; (IPC1-7): A61K31/70; C07H19/067; C07H19/073

Attorney, Agent or Firm:

Kyozo Yuasa

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