Title:
NOVEL DERIVATIVES OF 4-PHENYL-4-OXO-2-BUTENOIC ACID AND THEIR SALTS, MANUFACTURE, USE AS DRUG AND COMPOSITION CONTAINING THEM
Document Type and Number:
Japanese Patent JPS5879950
Kind Code:
A
Abstract:
A compound of the formula I: (I) in which R1 and R2 in any position on the benzene ring are different from each other, and independently represent a hydroxy group or an alkoxy group containing from 1 to 8 carbon atoms, or else R1 and R2 together form an -OCH2CH2O-radical, and R represents a hydrogen atom or an alkyl group containing from 1 to 8 carbon atoms, as well as the alkali metal, alkaline earth metal, ammonium or amine salts of the said products of formula I in which R represents a hydrogen atom. These compounds have been found useful in the treatment of hyperchlorhydria, gastric and gastro-duodenal ulcers, gastritis, hiatal hernias, and gastric and gastro-duodenal ailments accompanied by gastric hyperacidity. Pharmaceutical compositions including these compounds are disclosed along with methods for their production.
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Inventors:
MARIO BIANKI
FUERUNANDO BARUTSUAGI
FUERUNANDO BARUTSUAGI
Application Number:
JP18480982A
Publication Date:
May 13, 1983
Filing Date:
October 22, 1982
Export Citation:
Assignee:
ROUSSEL UCLAF
International Classes:
A61K31/335; A61K31/357; A61P1/04; C07C51/00; C07C59/90; C07C67/00; C07C69/738; C07D319/08; C07D319/18; (IPC1-7): A61K31/335; C07C51/353; C07C51/373; C07C59/90; C07C69/738; C07D319/18
Attorney, Agent or Firm:
Motohiro Kurauchi
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