Title:
NOVEL DIHYDROXYBENZENE ETHER DERIVATIVES, MANUFACTURE AND USE AS DRUG
Document Type and Number:
Japanese Patent JPS58928
Kind Code:
A
Abstract:
An ether derivative of a dihydroxybenzene of the formula in which R1 is 1 to 3 identical or different substituents selected from hydrogen, halogen, trifluoromethyl, carboxyl, alkyl, alkoxy, alkylmercapto and carbalkoxy, with in each case 1 to 4 carbon atoms in the alkyl and alkoxy groups, and R2 and R3 are different and each is an alkyl or alkenyl chain in which 1 or 2 CH2 chain members are optionally replaced by O, S, CO or a phenylene group, and/or in which the chain is optionally substituted by 1 to 3 identical or different substituents selected from hydroxyl, halogen, trifluoromethyl, phenyl, carboxyl, alkyl, alkoxy, alkylmercapto, carbalkoxy, and acyl, the phenyl radical in turn optionally being substituted by halogen, trifluoromethyl, carboxyl, alkyl, alkoxy, alkylmercapto or carbaloxy, and the abovementioned alkyl, alkoxy and acyl groups in each case containing 1 to 4 carbon atoms, and in which at least one of the radicals R2 or R3 is substituted and/or in at least one of the radicals R2 or R3 1 or 2 chain members are replaced by 1 or 2 identical or different radicals selected from O, S, CO and phenylene, is effective in combating cardiac infarcations, angina pectoric, thromboembolic illnesses, in venous and arterial regions and arteriosclerosis.
Inventors:
HORUSUTO BESUHAAGEN
URURITSUHI HERURAIN
GERUTO RAINHARUTO
FURIIDERU ZOITAA
ERIZABETO PERUTSUBORUN
URURITSUHI HERURAIN
GERUTO RAINHARUTO
FURIIDERU ZOITAA
ERIZABETO PERUTSUBORUN
Application Number:
JP10627482A
Publication Date:
January 06, 1983
Filing Date:
June 22, 1982
Export Citation:
Assignee:
BAYER AG
International Classes:
A61K31/085; A61K31/19; A61K31/235; A61P7/02; A61P9/08; A61P9/10; C07C41/00; C07C43/17; C07C43/20; C07C69/92; C07C43/225; C07C51/00; C07C51/367; C07C59/31; C07C59/64; C07C59/68; C07C59/90; C07C65/24; C07C65/40; C07C67/00; C07C67/29; C07C69/618; C07C69/736; C07C69/76; C07C313/00; C07C323/20; (IPC1-7): A61K31/085; C07C43/17; C07C43/20; C07C59/31; C07C59/64; C07C69/736; C07C69/76; C07C69/92; C07C149/32
Domestic Patent References:
| JPS53105437A | 1978-09-13 | |||
| JPS5511577A | 1980-01-26 | |||
| JPS5536496A | 1980-03-14 | |||
| JPS5214734A | 1977-02-03 | |||
| JPS5095230A | 1975-07-29 | |||
| JPS56113722A | 1981-09-07 |
Attorney, Agent or Firm:
Heikichi Odashima