Title:
NOVEL HISTONE DEACETYLASE INHIBITOR
Document Type and Number:
Japanese Patent JP2014144947
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a compound that can inhibit histone deacetylase (HDAC) and is suitable as a therapeutic agent for diseases associated with cell proliferation such as malignant tumors.SOLUTION: This invention provides a novel stilbene-like compound such as N-(2-aminophenyl)-4-((3-(3,4-difluorophenyl)-2-(4-fluorophenyl)acrylamide)methyl)benzamide, and N-(2-aminophenyl)-4-((3-(4-methoxyphenyl)-2-(phenyl)acrylamide)methyl)benzamide.
Inventors:
SRIDHARAN RAJAGOPAL
VIRENDRA KACHHADIA
THANASEKARAN PONPANDIAN
ABDUL RAHEEM KEERI
UMAMAHESWARI MANI
SURESH RATHINASAMY
PRAVEEN RAJENDRAN
KAMARAJ MANI
BALAJI RAMACHANDRAN
PUNTHALIR NARAYANASWAMY
SRIRAM RAJAGOPAL
VIRENDRA KACHHADIA
THANASEKARAN PONPANDIAN
ABDUL RAHEEM KEERI
UMAMAHESWARI MANI
SURESH RATHINASAMY
PRAVEEN RAJENDRAN
KAMARAJ MANI
BALAJI RAMACHANDRAN
PUNTHALIR NARAYANASWAMY
SRIRAM RAJAGOPAL
Application Number:
JP2013220426A
Publication Date:
August 14, 2014
Filing Date:
October 23, 2013
Export Citation:
Assignee:
ORCHID CHEMICALS & PHARM LTD
International Classes:
C07C237/42; A61K9/08; A61K9/10; A61K9/12; A61K9/14; A61K9/20; A61K9/48; A61K31/165; A61K31/167; A61K31/175; A61K31/27; A61K31/36; A61K31/381; A61K31/4406; A61K31/4409; A61K31/47; A61P35/00; A61P43/00; C07C231/02; C07C239/14; C07C269/00; C07C271/20; C07C315/04; C07C317/50; C07C319/20; C07C321/28; C07D213/56; C07D215/12; C07D317/60; C07D333/24
Attorney, Agent or Firm:
Ueda Kunio
Takaharu Fujita
Miki Kawakami
Takaharu Fujita
Miki Kawakami