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Title:
NOVEL INHIBITOR OF MEPRIN ALPHA AND BETA
Document Type and Number:
Japanese Patent JP2023129525
Kind Code:
A
Abstract:
To provide a novel hydroxamic acid derivative as an inhibitor of meprin β and/or α, a pharmaceutical composition comprising such a compound, a method for treatment or prophylaxis of disease or a condition, especially such that are related to meprin. β and/or. α., and a compound and pharmaceutical composition for use in such a method.SOLUTION: A compound represented by a formula I, its individual enantiomers, its individual diastereomers, its hydrates, its solvates, its crystal forms, its individual tautomers, or a pharmaceutically acceptable salt thereof are provided.SELECTED DRAWING: None

Inventors:
MICHAEL WERMANN
MIRKO BUCHHOLZ
HANS-ULRICH DEMUTH
DANIEL RAMSBECK
DAGMAR SCHLENZIG
STEPHAN SCHILLING
Application Number:
JP2023117716A
Publication Date:
September 14, 2023
Filing Date:
July 19, 2023
Export Citation:
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Assignee:
VIVORYON THERAPEUTICS AG
International Classes:
C07C259/06; A61K31/16; A61K31/166; A61K31/195; A61K31/275; A61K31/36; A61K31/401; A61K31/4406; A61P1/04; A61P9/12; A61P11/00; A61P13/10; A61P13/12; A61P17/02; A61P25/28; A61P29/00; A61P35/00; A61P43/00; C07D207/16; C07D213/38; C07D317/58; C07D319/18; C07K5/02
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mihiro
Tatsuhiko Abe