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Title:
NOVEL RAT A
Document Type and Number:
Japanese Patent JPH11127878
Kind Code:
A
Abstract:

To provide a novel polynucleotide that has high identity to a nucleic acid encoding a rat A polypeptide containing a specific amino acid sequence, and is useful for screening of antibacterial compounds, treatment and diagnosis of Chlamydia trachomatis infections.

This is a polynucleotide having at least 70% identity to the polynucleotide encoding the polypeptide containing the amino acid sequence of the formula. This is a novel isolated polynucleotide containing the polynucleotide sequence comprising at least 70% identity to the polynucleotide encoding the same mature polypeptide as that expressed by the rat A gene included in Chlamydia trachomatis and is useful for screening of antibacterial compounds and for treatment and diagnosis of infections of Chlamydia trachomatis. This polypeptide is obtained by probing the chromosomal DNA library of Chlamydia trachomatis with the marker gene originating from its partial sequence.


Inventors:
BLACK MICHAEL TERENCE
REICHARD RAYMOND
Application Number:
JP23623398A
Publication Date:
May 18, 1999
Filing Date:
July 17, 1998
Export Citation:
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Assignee:
SMITHKLINE BEECHAM CORP
International Classes:
G01N33/50; A61K38/00; A61K39/00; A61K39/395; A61K45/00; A61K48/00; A61P31/04; A61P37/00; C07K16/40; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/10; C12N15/00; C12N15/09; C12N15/54; C12P21/02; C12P21/08; C12Q1/02; C12R1/645; (IPC1-7): C12N15/09; A61K38/00; A61K39/00; A61K39/395; A61K45/00; A61K48/00; C07K16/40; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02; C12Q1/02; G01N33/50
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)



 
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