To provide a novel polynucleotide that has high identity to a nucleic acid encoding a rat A polypeptide containing a specific amino acid sequence, and is useful for screening of antibacterial compounds, treatment and diagnosis of Chlamydia trachomatis infections.
This is a polynucleotide having at least 70% identity to the polynucleotide encoding the polypeptide containing the amino acid sequence of the formula. This is a novel isolated polynucleotide containing the polynucleotide sequence comprising at least 70% identity to the polynucleotide encoding the same mature polypeptide as that expressed by the rat A gene included in Chlamydia trachomatis and is useful for screening of antibacterial compounds and for treatment and diagnosis of infections of Chlamydia trachomatis. This polypeptide is obtained by probing the chromosomal DNA library of Chlamydia trachomatis with the marker gene originating from its partial sequence.
REICHARD RAYMOND