カルボキサミジンで修飾した単環式塩基を有するヌクレオシドアナログ

Japanese Patent JP4975930

B2

The inventions relates to the use of the carboxamidine of Formula 1, or a pharmaceutically acceptable salt thereof, for the manufacture of a medicament for the treatment of a Hepatitis C Virus (HCV) viral infection or a Hepatitis B Virus (HBV) viral infection, wherein the compound is in L-configuration or D-configuration.

JP6917978	A novel 6-6 bicyclic aromatic ring-substituted nucleoside analog for use as a PRMT5 inhibitor
JP2004035537	MODULATION OF EXPRESSION OF TH1 TYPE /TH2 TYPE CYTOKININ BY RIBAVIRIN AND RIBAVIRIN ANALOGUE IN ACTIVATED T LYMPHOCYTE

Robert Tam
Kanda Rama Sammy
The Hong
Johnson Lau

JP2001559475A

July 11, 2012

February 15, 2001

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Valeant Reseach & Development

A61K31/7056; A01P17/00; A61K31/70; A61K31/7052; A61K31/7068; A61K38/21; A61P1/16; A61P3/10; A61P17/00; A61P19/02; A61P25/00; A61P25/28; A61P29/00; A61P31/12; A61P31/14; A61P31/18; A61P33/00; A61P35/00; A61P37/02; A61P37/06; A61P43/00; C07H19/056; C07H19/14

Journal of Medicinal Chemistry,1973年,16(8),p.935-937
Journal of Medicinal Chemistry,1992年,35(17),p.3231-3238
The Lancet,1998年,351,p.83-87
Journal of Hepatology,1994年,21,p.145-150

Kyousei Tamura
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Shinichiro Yamanaka

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