Title:
O-ALPHA-GLYCOSIDE AND MANUFACTURE
Document Type and Number:
Japanese Patent JPS5745197
Kind Code:
A
Abstract:
Processes are provided for the synthesis of the human T-antigenic determinant 2-acetamido-2-deo×y-3-O-(β-D-galactopyranosyl)-a-D-galactopyranoside containing an a-0-glycosidically linked bridging arm O-(CH2)nCOR. The determinant is coupled to carrier molecules to form artificial T-antigens, and to insoluble supports to form T-immunoadsorbents. The artificial T-antigen is shown to elicit a delayed type hypersensitivity reaction as a diagnostic for the presence of cancer in humans.
Inventors:
LEMIEUX RAYMOND URGEL
RATCLIFFE ROBERT MURRAY
BAKER DONALD A
RATCLIFFE ROBERT MURRAY
BAKER DONALD A
Application Number:
JP10717881A
Publication Date:
March 13, 1982
Filing Date:
July 10, 1981
Export Citation:
Assignee:
CHEMBIOMED LTD
International Classes:
G01N33/53; A61K31/70; A61K39/00; C07H3/06; C07H15/04; G01N33/544; G01N33/569; G01N33/574; (IPC1-7): C07H15/04; G01N33/54
Domestic Patent References:
| JPS53130617A | 1978-11-14 |
Foreign References:
| US4137401A | 1979-01-30 |
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