Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
OINTMENT IN MOUTH
Document Type and Number:
Japanese Patent JPH0366612
Kind Code:
A
Abstract:

PURPOSE: To obtain an ointment in the mouth having excellent adhesion for many hours by blending an oily base with a compound capable of forming a complex thereof with a polyacrylic acid or a salt thereof.

CONSTITUTION: An oily base is blended with a compound capable of forming a complex thereof with a polyacrylic acid or a salt thereof, namely one or more of chitosan, polyvinyl pyrrolidone and polyvalent metallic salt and optionally an excipient, a surfactant, a solubilizer, etc., and pharmaceutically manufactured to give the objective substance. The objective substance contains 1-30% polyacrylic acid, 1-40% chitosan, 1-40% polyvinyl pyrrolidone or 0.01-30% polyvalent metallic salt. By the formation of the complex, the ointment itself is made into an insolubilized film, which can prevent elimination of the base, make a sustained release of drug and the objective substance can be administered without feeling of physical disorder like an ointment in the mouth molded into tablets or a lamellar state.


Inventors:
SHIMIZU TOSHITO
OKADA TAIZO
MORIOKA SHIGEO
Application Number:
JP20132089A
Publication Date:
March 22, 1991
Filing Date:
August 04, 1989
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
SATO PHARMA
International Classes:
A61K9/06; A61K47/02; A61K47/32; A61K47/36; (IPC1-7): A61K9/06; A61K47/02; A61K47/32; A61K47/36
Domestic Patent References:
JP2013036233A2013-02-21
JP2012087495A2012-05-10
JPH08199874A1996-08-06
JP2013189843A2013-09-26
Attorney, Agent or Firm:
Tajiro Taiji