OPTICAL RESOLUTION OF (+-)-1-(1-NAPHTHYL)ETHYLAMINE

Title:

OPTICAL RESOLUTION OF (+-)-1-(1-NAPHTHYL)ETHYLAMINE

Document Type and Number:

Japanese Patent JPS62175446

Kind Code:

A

Abstract:

PURPOSE: To improve purity and yield, by using optically active 2-phe nylpropionic acid readily available in a large amount at a low cost in optically resolving (±)-1-(1-naphthyl)ethylamine to afford the titled compound useful as a raw material for modifiers of carriers in columns for separating optically active substances, etc.

CONSTITUTION: Optically active 2-phenylpropionic acid is used as a resolving agent to optically resolve (±)-1-(1-naphthyl)ethylamine. The amount of the above-mentioned resolving agent to be used is preferably within the range of 0.7W1.0mol based on the raw material. If the above-mentioned optical resolution is carried out using a solvent, e.g. water, methanol, ethanol, acetone, etc., the aimed compound of higher purity is obtained.

Inventors:

NOHIRA HIROYUKI
SATO KAZUO
MURAI YOSHIYUKI

Application Number:

JP1508386A

Publication Date:

August 01, 1987

Filing Date:

January 27, 1986

Export Citation:

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Assignee:

DAICEL CHEM

International Classes:

C07B57/00; C07B31/00; C07C67/00; C07C209/00; C07C211/30; (IPC1-7): C07B57/00; C07C87/28

Domestic Patent References:

JPS57181021A	1982-11-08
JPS61126035A	1986-06-13

Foreign References:

US2996545A

1961-08-15

Attorney, Agent or Firm:

Furuya Kaoru

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