Title:
ORAL DRUG DELIVERY COMPOSITION COMPRISING OXALIPLATIN AND METHOD FOR PRODUCING THE SAME
Document Type and Number:
Japanese Patent JP2022160584
Kind Code:
A
Abstract:
To provide oral drug delivery compositions comprising oxaliplatin, and to provide methods for producing the same.SOLUTION: The present invention relates to an oral drug delivery composition, in which a complex by ionic bonding of a bile acid derivative, which is an oral absorption enhancer, and oxaliplatin is formed, so as to be contained in the internal aqueous phase of a water-in-oil-in-water (w/o/w) multiple emulsified nanoemulsion, thereby improving the oral bioavailability of oxaliplatin, a water-soluble anticancer drug, manufacturing oxaliplatin, which is currently administered only in injection form, into a dosage form that can be administered orally, reducing the inconvenience and problems caused by the use of injections, and enabling the contribution of improved patient compliance and reduced medical costs.SELECTED DRAWING: Figure 1
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Inventors:
Park Jin Woo
Byun Youngro
Choi Young Kwon
Chang Kwang-young
Lee Jae Bum
Byun Youngro
Choi Young Kwon
Chang Kwang-young
Lee Jae Bum
Application Number:
JP2022125209A
Publication Date:
October 19, 2022
Filing Date:
August 05, 2022
Export Citation:
Assignee:
ICURE BNP CO.,LTD.
International Classes:
A61K9/107; A61K47/54; A61K9/113; A61K31/12; A61K31/282; A61K31/352; A61K31/513; A61K31/519; A61K47/06; A61K47/08; A61K47/10; A61K47/12; A61K47/14; A61K47/26; A61K47/28; A61K47/34; A61K47/36; A61K47/42; A61P35/00
Attorney, Agent or Firm:
TRY International Patent Attorney Corporation