Title:
局所麻酔薬を含有する口中用または咽頭部用製剤
Document Type and Number:
Japanese Patent JP4669960
Kind Code:
B2
Abstract:
Provided is a drug formulation for mouth or pharynx to be used for medical care or treatment for serious stomatitis caused by a side effect of an anti-tumor agent or the like, and for anesthesia in the pharynx, with remarkably suppressed discomfort due to bitter taste although it contains a local anesthetic as a main efficacious component. The drug formulation of the present invention comprises a local anesthetic as an efficacious component, and a weak acid, its pharmaceutically acceptable salt or a mixture thereof, wherein the mixing ratio of the weak acid to the local anesthetic is 1:1 or more by mole ratio.
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Inventors:
Kenki Ishibashi
Hama Book Eri
Keiko Yamazaki
Yokoyama Hideki
Akihiko Hirata
Takashi Fujii
Hama Book Eri
Keiko Yamazaki
Yokoyama Hideki
Akihiko Hirata
Takashi Fujii
Application Number:
JP2004165653A
Publication Date:
April 13, 2011
Filing Date:
June 03, 2004
Export Citation:
Assignee:
Medrex Co., Ltd.
International Classes:
A61K31/167; A61K47/12; A61K9/00; A61K9/08; A61K31/095; A61K31/185; A61K31/24; A61K47/20; A61P1/02; A61P1/04; A61P23/02; A61P29/00
Domestic Patent References:
| JP2001010977A | ||||
| JP2002255852A | ||||
| JP2000505093A | ||||
| JP11501678A | ||||
| JP60246325A | ||||
| JP2001086941A | ||||
| JP2000204036A | ||||
| JP2000290199A |
Other References:
佐藤悦子 他,Studies on the Stability of Azunol Xylocain Oradol Gargle (OAKG).,病院薬学,1993年,Vol.19, No.3,p.196-202
安野伸浩 他,Stability and Clinical Application of Azunol Elase Xylocaine Gargle (AEXG) in Hospital Preparation.,病院薬学,1995年,Vol.21, No.4,p.327-334
安野伸浩 他,Stability and Clinical Application of Azunol Elase Xylocaine Gargle (AEXG) in Hospital Preparation.,病院薬学,1995年,Vol.21, No.4,p.327-334
Attorney, Agent or Firm:
Kyuichi Ueki
Tadashi Sugakawa
Osamu Futakuchi
Hiroaki Ito
Tadashi Sugakawa
Osamu Futakuchi
Hiroaki Ito