Title:
オキサジアゾール化合物、ならびにそれらの製造および用途
Document Type and Number:
Japanese Patent JP2013520490
Kind Code:
A
Abstract:
The present invention relates to oxadiazole compounds in all their stereoisomeric and tautomeric forms and mixtures thereof in all ratios; and their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutically acceptable prodrugs and pharmaceutically acceptable polymorphs. The invention also relates to processes for the manufacture of the oxadiazole compounds and to pharmaceutical compositions containing them. The said compounds and their pharmaceutical compositions are useful in the treatment of cancer, particularly chronic myeloid leukemia (CML). The present invention further provides a method of treatment of cancer by administering a therapeutically effective amount of said compounds or their pharmaceutical compositions, to a mammal in need thereof.
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Inventors:
Shiva Kumar, Minax
Joshi, Kalpana, Sanjay
Aware, Balmic, Sopan
Sarde, Ankush, Gangaram
Bugle, sandeep, mukunda
Manohar, Sonar, Mohan
Joshi, Kalpana, Sanjay
Aware, Balmic, Sopan
Sarde, Ankush, Gangaram
Bugle, sandeep, mukunda
Manohar, Sonar, Mohan
Application Number:
JP2012554461A
Publication Date:
June 06, 2013
Filing Date:
February 24, 2011
Export Citation:
Assignee:
Piramal Enterprises Limited
International Classes:
C07D271/06; A61K31/4439; A61K31/454; A61P35/00; A61P35/02; A61P43/00; C07D413/04; C07D413/06; A61K31/4245
Attorney, Agent or Firm:
Hirokazu Miyazono