ＰＡＲ４阻害剤の結晶体 - BRISTOL-MYERS SQUIBB COMPANY

Title:

ＰＡＲ４阻害剤の結晶体

Document Type and Number:

Japanese Patent JP7473554

Kind Code:

B2

Abstract:

The present invention relates to co-crystals of the compound of formula (I), wherein the co-former molecule is succinic acid or citric acid, processes for the preparation of the co-crystal, pharmaceutical compositions thereof, and methods of using the co-crystals for treating or preventing thromboembolic disorders.

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Inventors:

Shram, Roxana F
Cunière, Nicola
Mubachu, Victoria Ray
Shi, John Pin
Brahova, Petinka Eye

Application Number:

JP2021535787A

Publication Date:

April 23, 2024

Filing Date:

December 20, 2019

Export Citation:

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Assignee:

BRISTOL-MYERS SQUIBB COMPANY

International Classes:

C07D513/04; A61K31/433; A61P7/02; A61P43/00

Domestic Patent References:

JP2015514808A

Other References:

高田則幸,Cocrystalのスクリーニングと原薬物性改善への応用,Pharm Tech Japan,2009年,Vol. 25, No.12,p.155-166
TILBORG, A. et al.,European Journal of Medicinal Chemistry,2014年,Vol. 74,pp. 411-426

Attorney, Agent or Firm:

Norito Yamao
Nagatoshi Shinagawa
Futami Kamahira
Masahiro Suwon
Wu Yingyan

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