Title:
PYRROLIDINE DERIVATIVES AS OXYTOCIN/VASOPRESSIN V1a RECEPTOR ANTAGONISTS
Document Type and Number:
Japanese Patent JP2021193084
Kind Code:
A
Abstract:
To provide efficient and oral, selective OT-R antagonist for treatment of diseases related to preterm labor.SOLUTION: The present invention relates to (3Z,5S)-5-(hydroxymethyl)-1-[(2'-methyl-1,1'-biphenyl-4-yl)carbonyl]pyrrolidin-3-one O-methyloxime and/or an active metabolite thereof having antagonist action on the oxytocin receptor and/or vasopressin V1a receptor, and to processes for their preparation, pharmaceutical compositions containing them and their use.SELECTED DRAWING: None
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Inventors:
ANDRE CHOLLET
Application Number:
JP2021113187A
Publication Date:
December 23, 2021
Filing Date:
July 07, 2021
Export Citation:
Assignee:
OBSEVA SA
International Classes:
C07D207/22; A61K31/40; A61K31/573; A61K33/06; A61K45/00; A61P9/00; A61P13/08; A61P15/00; A61P15/06; A61P15/08; A61P25/18; A61P43/00
Attorney, Agent or Firm:
Longhua International Patent Service Corporation
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