PARATHORMONE PRODUCTION PROMOTER CONTAINING VITAMIN D3 DERIVATIVE

Title:

PARATHORMONE PRODUCTION PROMOTER CONTAINING VITAMIN D3 DERIVATIVE

Document Type and Number:

Japanese Patent JPH1135470

Kind Code:

A

Abstract:

To obtain a parathormone production promoter capable of being orally administered for hypoparathyroidism and cartilaginous metabolic disorder by formulating a specific compound having an antagonistic action as an active ingredient.

This parathormone production promoter contains an active vitamin D3 antagonist as an active ingredient. The active vitamin D3 antagonist used herein is e.g. a compound of the formula [(m) is 0-3; (n) is 0 or 1; X is 0, S or NH; R1 and R2 are each H or a 1-4C alkyl], especially preferably (23 R)-1α-hydroxy-27-nor-25-methylene vitamin D3-26,23-lactone. The active ingredient is usually administered at a daily dose of 1-100 mg/person.

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Inventors:

MIURA DAISHIROU
TAKASE ATSUSHI
ISHIZUKA SEIICHI

Application Number:

JP19696997A

Publication Date:

February 09, 1999

Filing Date:

July 23, 1997

Export Citation:

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Assignee:

TEIJIN LTD

International Classes:

A61K31/59; A61P3/00; A61P5/12; A61P43/00; (IPC1-7): A61K31/59; A61K31/59

Attorney, Agent or Firm:

Maeda Junhiro

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