Title:
PEGYLATED ION CHANNEL MODULATING COMPOUND
Document Type and Number:
Japanese Patent JP2008214353
Kind Code:
A
Abstract:
To provide a polyethylene glycolated (PEGylated) ion channel modulating compound that meets the requirement of identification of new antiarrhythmic treatment in both of ventricular arrhythmia and atrial arrhythmia.
This invention is a PEGylated derivative of the ion channel modulating compound having one or more of the PEGylated parts connected to the ion channel modulating compound. In one embodiment, the PEG part is connected via linker to the ion channel modulating compound. The compound also can be connected to the PEG part by substituting any atomic valence of the compound bonded to the PEG part.
Inventors:
CHEU ELIZABETH L S
CHOI LEWIS SIU LEUNG
CHOU DOUG TA HUANG
DAVIDOFF ALLEN W
EZRIN ALAN M
JUNG GRACE
PLOUVIER BERTRAND M C
YIFRU AREGAHEGN
CHOI LEWIS SIU LEUNG
CHOU DOUG TA HUANG
DAVIDOFF ALLEN W
EZRIN ALAN M
JUNG GRACE
PLOUVIER BERTRAND M C
YIFRU AREGAHEGN
Application Number:
JP2008088708A
Publication Date:
September 18, 2008
Filing Date:
March 28, 2008
Export Citation:
Assignee:
CARDIOME PHARMA CORP
International Classes:
C07D207/12; A61K31/40; A61K47/48; A61K51/04; A61P9/06; A61P43/00; C07C257/06; C07D209/88; C07D209/94; C07F9/572; C07H15/203
Domestic Patent References:
| JP2002509908A | 2002-04-02 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita