エリトロポエチン受容体のためのペプチドリガンド

Title:

エリトロポエチン受容体のためのペプチドリガンド

Document Type and Number:

Japanese Patent JP4361684

Kind Code:

B2

Abstract:

Clones isolated from phage display libraries that bound to an erythropoietin (EPO) receptor probe are disclosed. Peptides encoded by sequences of those clones that bound to the EPO receptor are disclosed. A 12-mer amino acid consensus sequence, CXXGWVGXCXXW (where X represents one of many amino acids), common to the peptides that bound to the EPO receptor, but unrelated to the primary structure of EPO, is disclosed.

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Inventors:

McConnell, Stephen Jay.
Spinella, Dominique.

Application Number:

JP2000536391A

Publication Date:

November 11, 2009

Filing Date:

March 17, 1999

Export Citation:

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Assignee:

Chugai Pharmaceutical Co., Ltd.

International Classes:

C07K7/08; C12N15/09; A61K38/00; A61K45/00; A61P7/06; A61P43/00; C07K1/04; C07K7/64; C07K14/505; C07K14/71; C07K19/00; C12Q1/68

Other References:

Science, vol.273, pp.458-463 (1996)

Attorney, Agent or Firm:

Takashi Ishida
Jun Tsuruta
Fukumoto product
Masaya Nishiyama
Higuchi Souji

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