Title:
ペプチドの製造方法
Document Type and Number:
Japanese Patent JP3579038
Kind Code:
B2
Abstract:
The present invention relates to a process for the preparation of peptides using an excess of an activated carboxylic component to acylate an amino component, wherein after the acylation an amine comprising a free anion or a latent anion is used as a scavenger of residual activated carboxylic functions. This process is useful for the preparation of oligo- and polypeptides and, more generally, in the preparation of compounds containing one or more amide bonds.
Inventors:
Ivo Franci Etzgen
Paulus Bernardus Wilhelms Ten Cortenal
Paulus Bernardus Wilhelms Ten Cortenal
Application Number:
JP2002197549A
Publication Date:
October 20, 2004
Filing Date:
July 05, 2002
Export Citation:
Assignee:
Akzo Novel N B
International Classes:
C07K1/02; C07K1/04; C07K1/08; C07C231/02; C07K5/06; C07K5/072; (IPC1-7): C07K1/08; C07K1/02
Domestic Patent References:
| JP64022897A |
Other References:
J.Org.Chem.,Vol.64,No.12(1999)p.4324-4338
Attorney, Agent or Firm:
Yoshio Kawaguchi