Title:
PEPTIDYL HETEROCYCLE
Document Type and Number:
Japanese Patent JPH01221357
Kind Code:
A
Abstract:
NEW MATERIAL: A compd. of formula I [where A is H, alkyl, aminoalkyl, phenylalkyl, a heterocycle or the like; W is CO, CHOH or NR2m (R2m is H or alkyl); U is CO, CH2 or NR2m; V is C, C(OH) or the like; R1 is alkyl, benzyl, phenetyl or the like; R3 is H or NH2; and Z is formula II (where M is O, S or the like; T is CO, CS, S or the like; E is O, S or the like; and G is absent or is CH2 or the like) or the like].
EXAMPLE: (2R)-2-beznyl-3-thiazole-4-isopropionyl-L-(4-thiazolyl)-Ala amide of (2'S,1'R,5S)-3-ethyl-5-(1'-hydroxy-2'-amino-3'-cyclohexylpropyl)-oxazolidin-2-one.
USE: A drug for treating hypertension.
PROCESS: The compd. of formula I is obtd., e.g. by reacting a compd. of formula III with a compd. of formula IV.
Inventors:
SOURU HAWAADO ROOZENBAAGU
JIYOSEFU EFU DERARIA JIYUNIA
HIN RIYUN SHIYAMU
DEIRU JIEI KENPUFU
UIRIAMU AARU BEEKAA
JIYOSEFU EFU DERARIA JIYUNIA
HIN RIYUN SHIYAMU
DEIRU JIEI KENPUFU
UIRIAMU AARU BEEKAA
Application Number:
JP23143088A
Publication Date:
September 04, 1989
Filing Date:
September 14, 1988
Export Citation:
Assignee:
ABBOTT LAB
International Classes:
A61K31/395; A61K31/415; A61K31/42; A61K31/421; A61K31/535; A61K31/536; A61K31/5375; A61K31/5377; A61K31/538; A61K31/54; A61P9/12; C07C67/00; C07C69/24; C07C213/00; C07C215/10; C07C215/20; C07C215/28; C07C217/08; C07C217/28; C07C229/22; C07C229/26; C07C229/30; C07C229/32; C07C229/34; C07C229/36; C07C231/00; C07C231/02; C07C271/10; C07C233/11; C07C233/22; C07C233/40; C07C233/47; C07C233/51; C07C235/20; C07C237/12; C07C237/20; C07C239/20; C07C255/46; C07C265/02; C07C265/04; C07C271/16; C07C271/20; C07C271/22; C07C275/24; C07C317/28; C07C317/44; C07C317/48; C07C323/24; C07C323/41; C07C323/56; C07C323/59; C07C323/60; C07D207/12; C07D211/76; C07D213/40; C07D233/32; C07D233/61; C07D263/04; C07D263/06; C07D263/16; C07D263/22; C07D263/24; C07D263/28; C07D265/10; C07D273/04; C07D277/24; C07D285/10; C07D295/12; C07D295/13; C07D295/185; C07D295/205; C07D295/215; C07D295/22; C07D309/14; C07D319/06; C07D413/06; C07D413/12; C07D413/14; C07D417/12; C07D417/14; C07D521/00; C07K5/02; C07K5/06; C07K5/065; C07K5/08; A61K38/00; (IPC1-7): A61K31/395; A61K31/415; A61K31/42; A61K31/535; A61K31/54; C07; C07C69/24; C07C91/10; C07C91/23; C07C93/04; C07C101/30; C07C101/34; C07C102/00; C07C102/04; C07C103/50; C07C103/58; C07C103/76; C07C119/048; C07C121/80; C07C125/065; C07C149/23; C07C149/24; C07D207/12; C07D233/61; C07D263/22; C07D263/24; C07D265/10; C07D273/04
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)
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