Title:
灌流臓器止血法
Document Type and Number:
Japanese Patent JP2010512230
Kind Code:
A
Abstract:
Disclosed are compositions, methods and kits to control bleeding through the use of an internal occluder based on polymeric solutions, including use of reverse thermosensitive polymers in nephron-sparing surgeries, which produces a completely bloodless surgical field, allowing speedy resection. In certain embodiments, after a certain amount of time, the flow gradually resumes, with no apparent adverse consequences to the kidney. In certain embodiments, return of blood flow may be accelerated by cooling the kidney. The compositions, methods and kits for perfusive organ hemostasis can also be used to simplify or to enable other organ surgeries or interventional procedures, including liver surgery, prostate surgery, brain surgery, surgery of the uterus, spleen surgery and any surgery on any highly vascularized organs.
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Inventors:
Vogel, Jean-Marie
Wilkie, James A
Madras, Peter N
Wilkie, James A
Madras, Peter N
Application Number:
JP2009541532A
Publication Date:
April 22, 2010
Filing Date:
December 11, 2007
Export Citation:
Assignee:
PLUROMED, INC.
THE LAHEY CLINIC, INC.
THE LAHEY CLINIC, INC.
International Classes:
A61L17/00
Domestic Patent References:
| JP2006521177A | 2006-09-21 |
Foreign References:
| WO2005037062A2 | 2005-04-28 |
Other References:
JPN6012067407; Ｂｏｏｄｈｗａｎｉ Ｍ: 'Ｅｆｆｅｃｔｓ ｏｆ ｐｕｒｉｆｉｅｄ ｐｏｌｏｘａｍｅｒ ４０７ ｇｅｌ ｏｎ ｖａｓｃｕｌａｒ ｏｃｃｌｕｓｉｏｎ ａｎｄ ｔｈｅ ｃｏｒｏｎａｒｙ ｅｎｄｏｔｈｅｌｉｕｍ．' Ｅｕｒ Ｊ Ｃａｒｄｉｏｔｈｏｒａｃ Ｓｕｒｇ． ２９（５）, 200605, ７３６-４１
Attorney, Agent or Firm:
Yanagita Seiji
Go Sakuma
Go Sakuma