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Title:
PERSULFATED OLIGOSACCHARIDE ACTING ON SELECTIN AND CHEMOKINE
Document Type and Number:
Japanese Patent JP2004059506
Kind Code:
A
Abstract:

To provide a saccharide compound achieving regulation or the like of a bond between each of L-selectin, P-selectin and chemokine, and its ligand; and to provide a treating and preventing agent for ameliorating a symptom of a disease such as an inflammatory disease and exhibiting high affinity in a living body.

The treating and preventing agent is the saccharide compound represented by formulas (I) (wherein, R1, R2, R3 and R4 are each a hydrogen atom or a sulfonic acid group), (II) (wherein, R5, R6, R7 and R8 are each a hydrogen atom or a sulfonic acid group), (III) (wherein, R9 and R10 are each a hydrogen atom or a sulfonic acid group; and m is 3 or 4) or (IV) (wherein, R11 and R12 are each a hydrogen atom or a sulfonic acid; and n is 3 or 4), or contains the saccharide compound.


Inventors:
MIYASAKA MASAYUKI
KAWASHIMA HIROTO
Application Number:
JP2002220301A
Publication Date:
February 26, 2004
Filing Date:
July 29, 2002
Export Citation:
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Assignee:
TAISHO PHARMACEUTICAL CO LTD
International Classes:
A61K31/702; A61P9/00; A61P29/00; A61P35/04; A61P37/08; A61P43/00; C07H11/00; C12P11/00; C07H13/04; C12P19/14; (IPC1-7): C07H13/04; A61K31/702; A61P9/00; A61P29/00; A61P35/04; A61P37/08; A61P43/00
Attorney, Agent or Firm:
Yoshinori Hosoda