Title:
PHARMACEUTICAL COMPOSITION CONTAINING CORTICOTROPIN RELEASING FACTOR ANTAGONIST
Document Type and Number:
Japanese Patent JP2000001434
Kind Code:
A
Abstract:
To obtain a pharmacological composition useful for the treatment of inflammatory diseases of mammals such as depression, stress-induced headache and allergy by including a specific pyridine compound, etc.
This pharmacological composition contains a compound of formula I, II or III (the dotted line is optional double bond; A is N or the like; B is NR1R2 or the like; G is O or the like; Y is CH or the like; R1 is a 1-6C alkyl which may have one or two 1-2C alkyl groups or the like as substituents and may contain one C-C double bond or the like; R2 is a 1-12C alkyl or the like which may have 1-3 chlorine, etc., as substituents and may contain one C-C double bond, etc.; R3 is methyl or the like; R4 is H or the like; R5 is phenyl or the like which may have 1-3 fluorine atoms, etc., as substituents; R6 is H or the like; R16, and R17 are each H or the like) [e.g. 4-(1-ethyl-propoxy)-2,5- dimethyl-6-(2,4,6-trimethyl-benzyl)-pyrimidine] and its pharmacologically permissible carrier.
Inventors:
CHEN YUHPYNG L
Application Number:
JP16242599A
Publication Date:
January 07, 2000
Filing Date:
June 06, 1995
International Classes:
A61K31/00; A61K31/435; A61K31/4353; A61K31/437; A61K31/44; A61K31/4418; A61K31/4427; A61K31/443; A61K31/505; A61K31/52; A61K31/522; A61P1/00; A61P1/12; A61P1/14; A61P3/00; A61P3/04; A61P3/08; A61P3/10; A61P5/38; A61P11/00; A61P11/06; A61P17/00; A61P25/00; A61P25/04; A61P25/08; A61P25/16; A61P25/18; A61P25/20; A61P25/24; A61P25/26; A61P25/28; A61P29/00; A61P31/00; A61P31/12; A61P35/00; A61P37/00; A61P37/08; A61P39/00; A61P39/02; C07D213/69; C07D213/71; C07D213/89; C07D213/74; C07D213/80; C07D239/26; C07D239/34; C07D239/38; C07D239/42; C07D239/48; C07D239/50; C07D239/52; C07D401/04; C07D401/12; C07D405/12; C07D471/04; C07D473/22; C07D473/28; C07D473/32; C07D473/34; C07D473/40; C07D487/04; (IPC1-7): A61K31/44; A61P1/00; A61P1/14; A61P1/12; A61P3/04; A61P3/00; A61P3/10; A61P5/38; A61P11/06; A61P17/00; A61P25/00; A61P25/20; A61P25/08; A61P25/24; A61P25/28; A61P25/16; A61P25/04; A61P29/00; A61P31/12; A61P35/00; A61P37/00; A61P37/08; A61P39/02; A61K31/437; A61K31/505; A61K31/52
Foreign References:
| WO1994013677A1 | 1994-06-23 | | | |
| WO1994013676A1 | 1994-06-23 | | | |
| WO1995010506A1 | 1995-04-20 | | | |
Attorney, Agent or Firm:
Kazuo Shamoto (4 outside)
