PHARMACEUTICAL COMPOSITION CONTAINING SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVE

Japanese Patent JP2006298924

A

To provide new pharmaceutical compositions involved in treating lipid disorders (dyslipidemias) whether or not associated with insulin resistance.

The S enantiomer of a compound of formula(I) (wherein, R1 is 2,4-difluorophenyl or cyclohexyl) as well as pharmaceutically acceptable salts, solvates, crystalline forms and prodrugs thereof are provided, respectively. Use of the above in treating clinical conditions including lipid disorders (dyslipidemias) whether or not associated with insulin resistance, methods for their therapeutic use and the new pharmaceutical compositions containing them, are also provided, respectively.

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LINDSTEDT EVA-LOTTE ALSTERMARK
OLSSON ANNA CHRISTINA
LI LANNA

JP2006123399A

November 02, 2006

April 27, 2006

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ASTRAZENECA AB

A61K31/192; A61K45/00; A61K31/16; A61K31/195; A61K31/40; A61K31/505; A61K31/554; A61K45/06; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P5/48; A61P5/50; A61P9/04; A61P9/10; A61P9/12; A61P9/14; A61P13/12; A61P15/00; A61P15/08; A61P25/00; A61P25/16; A61P25/28; A61P27/02; A61P35/00; A61P43/00; C07C69/734; C07C69/736; C07C231/12; C07C235/20; C07D235/20

Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Takumi Terachi

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